Systemic Markers of Inflammation and Cognitive Decline in Old Age
نویسندگان
چکیده
منابع مشابه
Subclinical Thyroid Dysfunction and Cognitive Decline in Old Age
BACKGROUND Subclinical thyroid dysfunction has been implicated as a risk factor for cognitive decline in old age, but results are inconsistent. We investigated the association between subclinical thyroid dysfunction and cognitive decline in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). METHODS Prospective longitudinal study of men and women aged 70-82 years with pre-e...
متن کاملGeneralized atherosclerosis, cognitive decline, and depressive symptoms in old age.
BACKGROUND Atherosclerosis may be linked to cognitive decline and depression in old age. METHODS The Leiden 85-Plus Study is a prospective population-based study of 599 subjects from age 85 onward. The generalized atherosclerotic burden was rated by the number of cardiovascular pathologies at baseline, as assessed by history taking from treating physicians and EKG. Cardiovascular pathologies ...
متن کاملTDP-43 pathology, cognitive decline, and dementia in old age.
IMPORTANCE Cognitive decline is a leading cause of disability and death in old age but its neurobiological bases are not well understood. OBJECTIVE To test the hypothesis that transactive response DNA-binding protein 43 (TDP-43) is related to late-life cognitive decline. DESIGN, SETTING, AND PARTICIPANTS Longitudinal clinical-pathologic cohort study involving more than 40 Catholic groups ac...
متن کاملAlcohol consumption and cognitive decline in early old age
OBJECTIVE To examine the association between alcohol consumption in midlife and subsequent cognitive decline. METHODS Data are from 5,054 men and 2,099 women from the Whitehall II cohort study with a mean age of 56 years (range 44-69 years) at first cognitive assessment. Alcohol consumption was assessed 3 times in the 10 years preceding the first cognitive assessment (1997-1999). Cognitive te...
متن کاملAge-associated cognitive decline in healthy old people.
BACKGROUND disease often confounds the identification of risk factors for age-associated cognitive decline in elderly subjects. If the cognitive effects of ageing are to be distinguished from those of disease, healthy people need to be studied. METHODS we examined the effects of incident disease and drug prescription on cognitive change in a sample of initially healthy old people in a longitu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American Geriatrics Society
سال: 2007
ISSN: 0002-8614,1532-5415
DOI: 10.1111/j.1532-5415.2007.01159.x